Turning service delivery into evidence that scales
Every clinic day, screening campaign and water point we run is also a chance to learn what works, for whom and at what cost. Our research hub turns that learning into evidence health systems can act on.
Vector-borne and neglected tropical diseases, and sickle cell
Malaria (reactive case detection, micro-stratification, vaccine uptake), sickle cell disease, and schistosomiasis and soil-transmitted helminths through WASH integration.
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Pillar 1
Malaria elimination & vector control
Focus: evaluating the real-world feasibility of reactive case detection (RCD), GIS micro-stratification and targeted vaccine deployment across high-burden and border transmission zones.
Key approach: integrating ultra-sensitive diagnostic protocols (LAMP / hsRDTs) into routine community outreach.
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Pillar 2
Neglected tropical diseases (NTDs) & WASH
Focus: assessing integrated delivery models for schistosomiasis, soil-transmitted helminths (STHs), other priority NTDs and water infrastructure in rural communities.
Key approach: combining clean-water hardware installation with community-led behavioural interventions.
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Pillar 3
Sickle cell disease & chronic care delivery
Focus: identifying health-workforce and supply-chain bottlenecks in early infant diagnosis, hydroxyurea adherence and routine screening.
Key approach: operationalising point-of-care diagnostics at primary healthcare facilities.
How we study delivery, not just disease
Health systems & bottleneck analysis
Evaluating health-workforce distribution and supply-chain logistics that decide whether an intervention reaches people.
Molecular & diagnostic innovation
Rapid diagnostic testing, surveillance workflows and the field feasibility of new diagnostics.
Community & behavioural insights
Community engagement (CEI) to drive vaccine uptake and treatment adherence.
Studies in our portfolio
Protocol details are published here once ethics approval is in place.
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Malaria
Community-led reactive case detection in border districts
- Sites
- Mbale, Pallisa and cross-border corridors
- Objective
- Feasibility of RCD with ultra-sensitive diagnostics
- Sample size
- To be published
- Population
- To be published
- Primary outcome
- To be published
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Sickle cell disease
Point-of-care sickle cell screening in routine antenatal care
- Sites
- Same Day Hospital Mbale and partner facilities
- Objective
- Integrating screening and early infant diagnosis into ANC
- Sample size
- To be published
- Population
- To be published
- Primary outcome
- To be published
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NTDs & WASH
Integrated WASH and NTD surveillance
- Sites
- Rural communities around Mt. Elgon
- Objective
- Water infrastructure plus community-led behaviour change
- Sample size
- To be published
- Population
- To be published
- Primary outcome
- To be published
Study site map
Our clinical hub, outreach districts, proposed research sites and cross-border surveillance zones. Markers show district or town centres, not exact facility locations.
How we measure implementation: RE-AIM
Every study reports against the five RE-AIM dimensions. Figures appear here as they are verified.
- R
Reach
Share of the intended population that takes part.
To be published - E
Effectiveness
Impact on health outcomes, including unintended effects.
To be published - A
Adoption
Facilities and staff willing to deliver the intervention.
To be published - I
Implementation
Fidelity, cost and adaptations in delivery.
To be published - M
Maintenance
Whether results and delivery last over time.
To be published
Accelerate evidence-based health solutions
Whether you are a donor, research institution or public health practitioner, explore how we can collaborate on implementation research in East Africa.